Down’s screening was performed at the time of conception of the first child. Is it necessary for the second child?

Down’s screening, in fact, is called serological screening in medicine. It includes what we call Down’s syndrome screening, trisomy 21, trisomy 18 and trisomy 13. These are serious chromosomal abnormalities that lead to many fetal structural abnormalities. In serological screening, there are other suggestions besides these, because it needs to do biochemical measurements of pregnancy-related proteins, alpha-fetoprotein, HCG and so on. These abnormalities also indicate that there may be other chromosomal abnormalities, such as translocation or deletion of chromosomes other than these three pairs of chromosomes. These may also lead to serious deformities in children.

Therefore, whether she is young, pregnant in her twenties or pregnant in her thirties or over forties, serological screening is recommended, which is also known as Down’s screening.

Of course, the incidence of Down’s syndrome is high in pregnant women over 35 years of age and low in pregnant women under 35 years of age, but it does not mean that these diseases do not occur among the younger group of women.

So, whether it’s a second or a third pregnancy, Down’s screening is recommended medically.


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